Abstract

Diabetes mellitus is one of the the most common, oldest and non communicable chronic disease in India.Diabetes is a serious,  costly and heterogeneous metabolic disorder which ischaracterized by chronically elevated blood glucose levels (BGLs) and an inability to maintain BGL homeostasis. According to Indian council of medical research (ICMR, section 1,2005) diabetes is defined as a metabolic cum vascular syndrome of multiple etiologies factorise by hyperglycemia with disturbance of carbohydrate, protein and fat metabolism resulting from insulin deficiency or resistance to insulin or both.According to American diabetes association (ADA) diabetes is is defined as a group of metabolic diseases characterized by  inappropriate hyperglycemia resulting from defects in insulin secretion, insulin action or both.