Supply chain resilience has emerged as a critical priority for organizations navigating global disruptions and uncertainties. Advanced Enterprise Resource Planning (ERP) systems, such as Oracle NetSuite, offer transformative capabilities to strengthen supply chain operations through improved data integration, real-time monitoring, and predictive analytics. This study explores the role of Oracle NetSuite in enhancing supply chain resilience, focusing on its ability to mitigate risks, optimize operations, and adapt to dynamic challenges. By analyzing case studies and industry data, the research highlights how Oracle NetSuite empowers organizations to achieve a resilient and sustainable supply chain. The findings underscore its value in fostering agility, efficiency, and decision-making in complex supply chain ecosystems. This study provides actionable insights and a conceptual framework for leveraging advanced ERP systems to ensure supply chain resilience and business continuity.