Abstract

The aim of our work is to study the various aspects of the management of childhood cancers in Bangui. The mean annual incidence was 5.09 cases. The age ranged from 2 months to 15 years, with an average of 8.21 years, the 10 to 15 year age group (42.85%) being the most affected. The majority of patients consulted between the 2nd and 6th month of the disease. The most frequent localizations were maxillofacial (32.14%), abdominal (25%) and cervical (10.71%). Clinical signs were swelling (87.5%), anemia (82.14%), altered general status (69.64%) and adenopathy (55.35%). Cytoption (44.6%) was the most common type of sampling followed by biopsy (23.3%) and surgical specimens (19.6%). The lymphomas (58.9%) were the first with a predominance of Burkitt's lymphoma (81.82%), followed by sarcomas (12.5%) and leukemias (8.9%). Treatment included chemotherapy (26.78%), surgery (8.92%) and surgery associated with chemotherapy (8.92%). The survival of children was 23.21% at 3 months and 8.92% at 6 months. The loss of follow-up was 53.58% at 6 months of decline. The death rate was 26.79% at 3 months and 33.92% at 6 months, a relapse case (1.79%). The availability of anticancer drugs and follow-up of patients are important to improve the prognosis.